Mamelodi Sundowns and Zesco United are the last two remaining COSAFA sides in the African Champions League competition after they won through to the second round at the weekend.
South African side Sundowns managed a 1-1 draw in Congo against AC Leopards that gave them a 3-1 aggregate success.
Zambian champions Zesco lost 2-0 at Guinea club Horoya, but still advanced 4-3 on aggregate after a handsome home win in the first leg.
Sundowns now face DR Congo side AS Vita Club in the second round that will determine which eight sides advance to the group stages. Zesco have set up a meeting with Stade Malien.
But for the rest of the regions challengers in the competition it was a weekend of disappointment.
Mozambican side Ferroviário Maputo drew 1-1 with Vita Club at home but lost the tie 2-1 on aggregate, while Madagascar outfit CNaPS Sport lost 6-3 on aggregate to Wydad Casablanca despite winning the home leg 2-1.
Angola’s Recreativo do Libolo lost 2-0 to Egyptian giants Al Ahly in Cairo to go down on aggregate by the same scoreline, while Kaizer Chiefs drew 0-0 at ASEC Abidjan to lose 1-0 on aggregate.
It was a similar story in the African Confederation Cup where two sides from the COSAFA region made it to the next stage.
Sagrada Esperança of Angola were held to a 1-1 draw by Mozambique side Liga Desportiva de Maputo, but advanced 2-1 on aggregate.
And Zambian club ZANACO defeated Harare City 3-1 at home to win the tie 5-2.
The only other remaining COSAFA club in the competition, South Africa’s BidVest Wits, lost 4-3 at Tanzanian side Azam to go down 7-3 on aggregate.